Duodenal Ulcer
A duodenal ulcer is an open sore that forms on the lining of the duodenum, the first section of the small intestine just below the stomach. The burning or gnawing pain it causes typically strikes between meals and at night, and often eases temporarily after eating. Most cases trace back to infection with Helicobacter pylori bacteria or long-term use of anti-inflammatory painkillers (NSAIDs). H. H. pylori infection is a common cause of duodenal ulcers and related digestive complaints.
Key points
- Infection with Helicobacter pylori or prolonged NSAID use are the most frequent causes of this open sore in the duodenum.
- Pain often appears between meals and overnight, then eases for a while once food is eaten.
- Proton pump inhibitors such as rabeprazole cut acid secretion sharply, letting misoprostol protect the lining when NSAIDs continue.
Reducing acid and protecting the gut lining
Healing a duodenal ulcer requires lowering the acid load inside the stomach and, where relevant, shielding the gut wall from further damage. Proton pump inhibitors do both jobs well: rabeprazole is a PPI that cuts acid secretion sharply, allowing the ulcerated tissue to repair. When an ulcer has developed because of NSAID use, misoprostol can be added to reinforce the mucosal lining and reduce the risk of further injury. Both medicines sit within the broader digestive health catalogue.
Seek medical attention promptly if you notice black or tarry stools, vomit that looks like coffee grounds, or sudden severe abdominal pain. These can signal bleeding and need same-day assessment.
Further reading
What is a duodenal ulcer and what causes it?
A duodenal ulcer is an open sore on the lining of the duodenum, the first section of the small intestine just below the stomach. Most cases are caused by infection with Helicobacter pylori bacteria or long-term use of anti-inflammatory painkillers (NSAIDs).
What are the symptoms of a duodenal ulcer?
The main symptom is burning or gnawing pain that often appears between meals and at night. It may ease for a while after eating.
How is a duodenal ulcer treated?
Treatment aims to lower the acid load in the stomach and protect the gut wall. Proton pump inhibitors such as rabeprazole cut acid secretion sharply, and misoprostol can be added when NSAID use is involved to reinforce the mucosal lining.
When should I see a doctor about a duodenal ulcer?
Seek medical attention promptly if you notice black or tarry stools, vomit that looks like coffee grounds, or sudden severe abdominal pain. These can signal bleeding and need same-day assessment.
Which treatments for duodenal ulcers can I order?
The medicines listed for duodenal ulcers contain misoprostol and rabeprazole. Examples include Cytotec and Aciphex. Each product page lists the strengths and forms.
Are medicines for duodenal ulcers available over the counter in Thailand?
Yes, online. Yasabai does not ask for a prescription to order medicines for duodenal ulcers. We are an online store, not a dispensing pharmacy; we arrange your order and delivery on your behalf.
Ordering without a prescription →Do you deliver medicines for duodenal ulcers to Thailand?
Yes. Our pharmacy partners ship from India to Thailand and across Asia in discreet packaging. Standard Airmail takes up to 3 weeks; Express Tracked Courier takes up to 1 week.
How ordering works →