Ursodeoxycholic Acid
Ursodeoxycholic acid (including brands like Urso and Ursofalk) is a bile acid used to treat liver conditions and assist with the dissolution of gallstones. This medication is available in two distinct generic formulations, providing options for long-term health management. It remains a standard treatment choice for patients looking to improve bile flow and treat chronic cholestatic liver disease.
Key points
- This naturally occurring bile acid works by lowering the cholesterol content of bile, reducing the risk of new stones forming.
- It treats primary biliary cholangitis, biliary cirrhosis and gallstones that do not require surgical removal.
- Marketed as Urso and Ursofalk, it comes as a hard capsule or tablet for ongoing treatment.
- Oestrogen-containing medicines and some lipid-lowering drugs can make this bile acid less effective.
What is Ursodeoxycholic Acid?
Ursodeoxycholic acid is a naturally occurring bile acid that functions to regulate the composition of bile. It is utilised in various medications to alter bile chemistry, reducing the potential for crystal formation. As a class of medication, it provides a non-invasive approach to managing biliary and liver-related conditions.
What Ursodeoxycholic Acid is used for
This medication addresses Primary Biliary Cholangitis and Biliary Cirrhosis. It is also used for Gallstones which do not require immediate surgery, specifically contributing to the Dissolution of Gallstones. By modifying the gallbladder environment, it supports better digestive function and liver health.
How does Ursodeoxycholic Acid work?
The medication works by changing the composition of bile, primarily through lowering its cholesterol content. This makes bile less likely to form crystals and subsequent stones, while simultaneously improving bile flow within the liver and bile ducts. This mechanism supports regular liver function and reduces inflammation caused by stagnant bile.
Ursodeoxycholic Acid brands and forms
Brands such as Urso and Ursofalk are recognized options for patients requiring this bile acid. Within the Digestive Health category, this medication is typically available as a capsule, hard, or tablet. The choice between these forms often depends on individual preference regarding ease of swallowing and the specific formulation provided by the manufacturer.
Safety overview for Ursodeoxycholic Acid
What to check before using this medicine
Ensure that your liver function and gallbladder health are assessed. This medication is not suitable for individuals with complete bile duct obstruction or specific inflammatory bowel conditions.
Possible reactions and tolerability
Common reactions include gastrointestinal discomfort such as abdominal pain, nausea, or diarrhoea. These effects are often transient, but individuals should monitor for any persistent changes in digestive health.
Interactions and health factors
Certain medications, particularly oestrogen-containing drugs or specific lipid-lowering agents, may decrease the effectiveness of this bile acid. Product labelling and verified clinical sources remain the correct references for specific contraindications, interactions and reactions.
Further reading
What is ursodeoxycholic acid used for?
Ursodeoxycholic acid is used to treat primary biliary cholangitis and biliary cirrhosis, and for gallstones that do not require immediate surgery. It alters bile chemistry, contributing to the dissolution of gallstones.
How does ursodeoxycholic acid work?
Ursodeoxycholic acid is a naturally occurring bile acid that lowers the cholesterol content of bile, which makes bile less likely to form crystals and stones. It also improves bile flow and reduces inflammation caused by stagnant bile.
How long does ursodeoxycholic acid take to work?
Ursodeoxycholic acid usually takes 1 to 2 weeks to show its full effect. Treatment is then continuous.
What are the side effects of ursodeoxycholic acid?
Common side effects include diarrhoea, stool softening and abdominal pain, and some people may get elevated liver enzymes or urticaria. These effects are often transient, but you should monitor for any persistent changes and speak to a doctor or pharmacist if they continue.
Can ursodeoxycholic acid be taken with other medicines?
Certain medicines can affect it, particularly oestrogen-containing drugs and some lipid-lowering medicines, which may decrease its effectiveness. Antacids containing aluminium and cholestyramine also interact with it, so check with a doctor or pharmacist before combining medicines.
Who should not take ursodeoxycholic acid?
Ursodeoxycholic acid is contraindicated for those with hypersensitivity to bile acids, acute inflammation of the gallbladder, biliary obstruction or a non-functioning gallbladder. Your liver function and gallbladder health should be assessed first.
What ursodeoxycholic acid products are available?
Products containing ursodeoxycholic acid include Urso and Actigall. Compare forms, strengths and packs in the listings above.
Which brands contain ursodeoxycholic acid?
Besides the products listed here, ursodeoxycholic acid is sold under brand names such as Ursofalk. Names differ from country to country, so the active ingredient is the surest way to compare.
Can I buy ursodeoxycholic acid over the counter in Thailand?
Yes. In Thailand ursodeoxycholic acid is sold by pharmacists without a prescription, and Yasabai does not ask for one either. We are an online store, not a dispensing pharmacy; we arrange your order and delivery on your behalf.
Ordering without a prescription →Do you deliver ursodeoxycholic acid to Thailand?
Yes. Our pharmacy partners ship from India to Thailand and across Asia in discreet packaging. Standard Airmail takes up to 3 weeks; Express Tracked Courier takes up to 1 week.
How ordering works →