Esbriet
Pirfenidone 200mg and 400mg film-coated tablets, used in the management of idiopathic pulmonary fibrosis. An antifibrotic acting on growth factors.
- Category
- Respiratory Health
- Active ingredient
- Pirfenidone
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 200 · 400mg
You will receive a quality generic equivalent, depending on stock.
No prescription needed: we place your order for Esbriet on your behalf.
- Condition
- Idiopathic Pulmonary Fibrosis
- Therapeutic class
- Antifibrotic agent
- Pharmacological class
- Pyridine carboxylic acid derivative
- Minor side effects
- nausea; rash; fatigue; diarrhoea; dyspepsia; abdominal pain
- Moderate side effects
- photosensitivity reaction; pruritus; dizziness; headache; decreased appetite
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Originator
- Roche
- Onset time
- 2–4 weeks
- Duration
- long-term
- Storage instructions
- Store below 25°C, away from moisture and direct heat.
- Drug interactions
- fluvoxamine; ciprofloxacin; tobacco
- Age restrictions
- Not recommended for use in children or adolescents.
Contraindications
hypersensitivity to pirfenidone; severe hepatic impairment; severe renal impairment
Precautions and warnings
avoid sunlight and tanning lamps during treatment; monitor liver function regularly; photosensitivity reactions may occur
Serious side effects
elevated liver enzymes, requires immediate medical attention; angioedema, requires immediate medical attention
Patient summary
Pirfenidone 200mg and 400mg film-coated tablets, used in the management of idiopathic pulmonary fibrosis. An antifibrotic acting on growth factors.
Mechanism of action
Pirfenidone acts by modulating the production of growth factors and cytokines, reducing fibroblast proliferation and collagen synthesis in affected tissues, which helps slow the decline of lung function.
Pregnancy and breastfeeding
Pregnancy: Use is not recommended. Breastfeeding: Advised to discontinue breastfeeding during treatment.
Esbriet is a medication used to treat Idiopathic Pulmonary Fibrosis, containing the active ingredient Pirfenidone. It is supplied as a tablet in 200mg and 400mg strengths. The medicine is used to assist in managing the condition by helping to maintain respiratory function for those diagnosed with the disease.
Buying Esbriet online
While generic Pirfenidone, often manufactured in India, offers a more affordable alternative to the original brand, many patients prefer to order the original medication online to ensure consistency. This reliable access assists expats and residents across the region who may find it challenging to source specialised respiratory medicine when away from home.
What you will receive
Esbriet is the originator brand name, made by Roche. We use it here to identify the medicine only; we are not affiliated with Roche and do not ship the original Esbriet.
- You receive a generic equivalent: the same active ingredient (Pirfenidone) at the same dose, mostly recognised Indian branded generics from vetted manufacturers.
- The exact brand supplied depends on what is in stock at the dispatching warehouse.
- A regulated generic matches the original ingredient for ingredient by legal standard.