Hodgkin Lymphoma
Hodgkin lymphoma is a cancer arising from B lymphocytes in the lymph nodes. It is one of the more treatable blood cancers, cure rates exceed 85% in early-stage disease, and it tends to strike younger adults as well as people over 55.
Key points
- Persistent, non-tender swelling in a lymph node, often in the neck or under the arm, is typically the first noticeable sign.
- A trio of night sweats, fever and unintended weight loss together points to more advanced disease and matters for staging.
- Older patients or those unable to tolerate intensive regimens may instead receive an alkylating agent alongside radiotherapy for localised disease.
How Hodgkin Lymphoma Behaves and How It Is Treated
The classic sign is a painless, rubbery lump in the neck, armpit, or groin that does not resolve on its own. Drenching night sweats, unexplained weight loss, and persistent fever (together called B symptoms) point toward more advanced disease and carry staging significance. Fatigue and itch are common but easy to overlook.
Treatment is chemotherapy-based, most often multi-drug regimens. Alkylating agents such as chlorambucil have a place in certain presentations, particularly in older patients or those unsuitable for intensive protocols. Radiotherapy is often added for localised disease. Browse the broader oncology support category for related medicines.
If you notice a swollen lymph node that persists beyond two or three weeks, especially alongside any B symptom, seek medical review promptly.