Leukeran
Chlorambucil 2mg and 5mg film-coated tablets, used in the management of chronic lymphocytic leukaemia and Hodgkin and non-Hodgkin lymphoma.
- Category
- Oncology Support
- Active ingredient
- Chlorambucil
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 2 · 5mg
You will receive a quality generic equivalent, depending on stock.
No prescription needed: we place your order for Leukeran on your behalf.
- Therapeutic class
- Alkylating Agent
- Pharmacological class
- Nitrogen Mustard Derivative
- Contraindications
- hypersensitivity to chlorambucil; severe bone marrow suppression
- Minor side effects
- nausea; vomiting; diarrhoea
- Moderate side effects
- bone marrow suppression; stomatitis; elevated liver enzymes
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Originator
- Aspen Pharma
- Onset time
- 1–2 weeks
- Duration
- 3–4 weeks
- Storage instructions
- Store in a refrigerator at 2°C to 8°C. Keep in original packaging.
- Drug interactions
- live vaccines
- Age restrictions
- Not recommended for paediatric use.
Precautions and warnings
regular blood monitoring required during treatment; monitor for signs of infection
Serious side effects
secondary malignancies, requires immediate medical attention; interstitial lung disease, requires immediate medical attention; seizures, requires immediate medical attention
Patient summary
Chlorambucil 2mg and 5mg film-coated tablets, used in the management of chronic lymphocytic leukaemia and Hodgkin and non-Hodgkin lymphoma.
Mechanism of action
Chlorambucil is an alkylating agent. It binds to DNA within cells, causing cross-linking that prevents DNA replication and cell division. This process effectively inhibits the proliferation of abnormal, rapidly dividing cancerous cells, particularly those involved in lymphocytic disorders.
Pregnancy and breastfeeding
Pregnancy: Must not be used during pregnancy. Breastfeeding: Breastfeeding must be discontinued during treatment.
Leukeran is the pharmaceutical brand for Chlorambucil, widely used for the management of Chronic Lymphocytic Leukaemia, Hodgkin Lymphoma and Non-hodgkin Lymphoma. This treatment is supplied as tablets in 2mg and 5mg strengths. It serves as an established therapeutic option for these specific blood-related conditions.
Buying Leukeran online
Because this is a treatment for serious conditions, it is best used under a doctor’s care.
What you will receive
Leukeran is the originator brand name, made by Aspen Pharma. We use it here to identify the medicine only; we are not affiliated with Aspen Pharma and do not ship the original Leukeran.
- You receive a generic equivalent: the same active ingredient (Chlorambucil) at the same dose, mostly recognised Indian branded generics from vetted manufacturers.
- The exact brand supplied depends on what is in stock at the dispatching warehouse.
- A regulated generic matches the original ingredient for ingredient by legal standard.