Glucovance
Metformin with glibenclamide as a film-coated tablet, used in the management of type 2 diabetes mellitus. A biguanide paired with a sulfonylurea.
- Category
- Diabetes Management
- Active ingredients
- Metformin · Glibenclamide
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 400/2.50 · 500/5mg
You will receive a quality generic equivalent, depending on stock.
No prescription needed: we place your order for Glucovance on your behalf.
- Condition
- Type 2 Diabetes Mellitus
- Therapeutic class
- Biguanide Antidiabetic; Sulfonylurea
- Pharmacological class
- Biguanide; Sulfonylurea
- Contraindications
- hypersensitivity; severe renal impairment; diabetic ketoacidosis; diabetic coma
- Precautions and warnings
- monitor kidney function regularly; risk of lactic acidosis
- Minor side effects
- nausea; diarrhoea; abdominal pain
- Moderate side effects
- hypoglycaemia; headache; dizziness
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Originator
- Merck Serono
- Onset time
- 1–2 hours
- Duration
- 12–24 hours
- Storage instructions
- Store in a cool, dry place away from direct light and moisture.
- Drug interactions
- Alcohol; Cimetidine
- Age restrictions
- Not indicated for use in children.
Serious side effects
lactic acidosis, requires immediate medical attention; anaphylaxis, requires immediate medical attention
Patient summary
Metformin with glibenclamide as a film-coated tablet, used in the management of type 2 diabetes mellitus. A biguanide paired with a sulfonylurea.
Mechanism of action
This medicine combines two active agents: one that lowers liver glucose production and intestinal absorption, and another that stimulates the pancreas to release more insulin. Together, they help maintain balanced blood sugar levels in patients who have not achieved adequate control through diet or exercise alone.
Pregnancy and breastfeeding
Pregnancy: Use is generally avoided; insulin is preferred for blood glucose control. Breastfeeding: Not recommended as safety data is limited.
Glucovance combines Metformin and Glibenclamide to assist in the treatment of Type 2 Diabetes Mellitus. This medication comes as a tablet in strengths of 400/2.50mg and 500/5mg. It provides an established option for individuals requiring dual-agent support to help manage blood glucose levels effectively.
Buying Glucovance online
Generic versions of Metformin and Glibenclamide, largely produced in India, provide a significantly more affordable option than the original brand for expats and travelers who find themselves far from reliable local health sources.
Is Glucovance the original brand?
Yes, Glucovance is the originator brand name, made by Merck Serono. Yasabai uses it to identify the medicine; what you receive is a generic with the same active ingredients (metformin and glibenclamide) at the same doses, mostly a recognised Indian branded generic. The exact brand depends on stock.
How much does Glucovance cost?
It depends on the strength and pack. Glucovance comes in 400/2.50 and 500/5mg strengths, in packs of 30 to 360 tablets, and the price per tablet for every option is shown above, in US dollars or the currency you choose. Larger packs cost less per tablet. Paying with Bitcoin or Ethereum gives you an extra 10% off.
What is Glucovance used for?
Glucovance contains metformin and glibenclamide, used for type 2 diabetes mellitus. Glucovance combines two active agents: one that lowers liver glucose production and intestinal absorption, and another that stimulates the pancreas to release more insulin.
When does Glucovance start working?
Metformin and glibenclamide usually start to work within 1 to 2 hours, and their effect lasts about 12 to 24 hours. It varies from person to person.
What side effects can Glucovance cause?
The common side effects of metformin and glibenclamide are nausea, diarrhoea and abdominal pain. Less common ones include hypoglycaemia, headache and dizziness. Serious but less common side effects include lactic acidosis and anaphylaxis, which need urgent medical attention.
Does Glucovance interact with alcohol?
Alcohol can interact with metformin and glibenclamide, so check with a doctor or pharmacist before you drink while taking Glucovance. It can also interact with cimetidine.
Do I need a prescription to buy Glucovance in Thailand?
No. In Thailand metformin and glibenclamide are sold by pharmacists without a prescription, and Yasabai does not ask for one either. We are an online store, not a dispensing pharmacy; we arrange your order and delivery on your behalf.
Ordering without a prescription →Do you deliver Glucovance to Thailand?
Yes. Our pharmacy partners ship from India to Thailand and across Asia in discreet packaging. Standard Airmail takes up to 3 weeks; Express Tracked Courier takes up to 1 week.
How ordering works →What you will receive
Glucovance is the originator brand name, made by Merck Serono. We use it here to identify the medicine only; we are not affiliated with Merck Serono and do not ship the original Glucovance.
- You receive a generic equivalent: the same active ingredient (Metformin / Glibenclamide) at the same dose, mostly recognised Indian branded generics from vetted manufacturers.
- The exact brand supplied depends on what is in stock at the dispatching warehouse.
- A regulated generic matches the original ingredient for ingredient by legal standard.