Istamet
Istamet pairs sitagliptin with metformin in a film-coated tablet for type 2 diabetes mellitus, raising incretin levels alongside a biguanide.
- Category
- Diabetes Management
- Active ingredients
- Sitagliptin · Metformin
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 50/1000mg
You will receive a quality branded generic or generic, depending on stock.
No prescription needed: we place your order for Istamet on your behalf.
- Condition
- Type 2 Diabetes Mellitus
- Alternative names
- Janumet
- Therapeutic class
- Dipeptidyl Peptidase-4 (DPP-4) Inhibitor; Biguanide Antidiabetic
- Pharmacological class
- DPP-4 Inhibitor; Biguanide
- Minor side effects
- nausea; diarrhoea; headache
- Moderate side effects
- upper respiratory tract infection; nasopharyngitis
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Manufacturer
- Merck Sharp & Dohme
- Onset time
- 1–2 hours
- Duration
- 12–24 hours
- Storage instructions
- Store below 25°C, away from sunlight and moisture.
- Drug interactions
- Alcohol; Iodinated contrast media
- Age restrictions
- Not indicated for use in children or adolescents.
Contraindications
hypersensitivity to sitagliptin; hypersensitivity to metformin; severe renal impairment; diabetic ketoacidosis; severe hepatic impairment
Precautions and warnings
monitor renal function regularly; risk of lactic acidosis; discontinue if symptoms of pancreatitis occur
Serious side effects
pancreatitis, requires immediate medical attention; lactic acidosis, requires immediate medical attention; anaphylaxis, requires immediate medical attention
Patient summary
Istamet pairs sitagliptin with metformin in a film-coated tablet for type 2 diabetes mellitus, raising incretin levels alongside a biguanide.
Mechanism of action
This medicine combines two active agents that work by increasing incretin levels to stimulate insulin release after meals and by reducing glucose production in the liver, effectively lowering blood sugar levels.
Pregnancy and breastfeeding
Pregnancy: Should be avoided unless clearly necessary. Breastfeeding: Not recommended as components may pass into breast milk.
Istamet combines sitagliptin and metformin within a single tablet to help manage Type 2 Diabetes Mellitus. Also marketed internationally as Janumet, this dual-action medication is available in strengths including 50/1000mg. Patients relying on this combination for glycaemic control often select these branded oral treatments for their consistent formulation and reliability.
Buying Istamet online
For many expats and those living far from a well-stocked pharmacy, ordering this medication online provides a consistent way to maintain regular supplies. While branded versions remain common, many users also consider generic sitagliptin and metformin, much of it made in India, as a more affordable option for long-term health management.
What you will receive
Istamet is the name this medicine is listed under. What you receive is a branded generic or generic with the same active ingredient (Sitagliptin / Metformin) at the same dose.
- We supply branded generics and generics only, mostly recognised Indian branded generics from vetted manufacturers, not originator brand packs.
- The exact brand and manufacturer depend on what is in stock at the dispatching warehouse.