Levodopa
Levodopa is a standard medication associated with brands like Sinemet, Sinemet CR and Stalevo. This page lists 3 available products for addressing complex motor symptoms. As a precursor to dopamine, it is a primary treatment modality used to manage involuntary movement symptoms. Below you will find the available formulations.
Sinemet CR
Parkinson's Disease
25/100mg
Sinemet CR is carbidopa with levodopa 25/100mg in a modified-release tablet for Parkinson's disease, spreading the dose across a longer period.
Key points
- Crosses the blood-brain barrier and is converted into dopamine, replenishing the neurotransmitter that Parkinson’s disease depletes.
- Comes in several release profiles, including standard, prolonged-release and modified-release tablets, to help keep dopamine levels steady.
- Involuntary movements called dyskinesia can develop as the body adjusts, alongside a drop in blood pressure on standing.
What is Levodopa?
Levodopa is a pharmaceutical agent classified as an aromatic amino acid, used primarily to support motor function in neurological care. Because different individuals respond to varying release speeds and delivery methods, manufacturers produce multiple options, from standard tablets to modified-release formats. These variations allow for consistency in symptom management.
What Levodopa is used for
This medication is used for Parkinson’s Disease. It addresses motor symptoms by entering the central nervous system, where it converts into dopamine. By increasing dopamine concentrations in the brain, it supports the recovery of motor control in conditions affecting neuronal integrity.
How does Levodopa work?
Levodopa crosses the blood-brain barrier, a protective separation between circulating blood and the brain. Once inside, an enzyme converts the molecule into dopamine, a neurotransmitter essential for smooth, coordinated movement. This replenishment addresses the deficit caused by the disease, allowing for improved muscle function.
Levodopa brands and forms
Choosing the correct brand and format is a key part of Neurology treatment. Well-known options such as Sinemet, Sinemet CR, Caramet and Duodopa provide various pharmacological profiles. Patients and clinicians select between different release mechanisms, such as a Tablet, Prolonged-release tablet, Modified-release tablet, or Film-coated tablet, to maintain stable levels in the bloodstream throughout the day.
Safety overview for Levodopa
What to check before using this medicine
Verify that you understand the release mechanism of your specific tablet, as prolonged-release versions differ from standard ones. Ensure that your current medical history is thoroughly reviewed to avoid contraindications.
Possible reactions and tolerability
Common reactions may include nausea, dizziness, or orthostatic hypotension, which is a drop in blood pressure when standing. Sudden involuntary movements, known as dyskinesia, can also materialize as the body adjusts to the medication.
Interactions and health factors
Concurrent use of other medications, particularly certain blood pressure agents or antipsychotics, can alter the efficacy of Levodopa. Product labelling and verified clinical sources remain the correct references for specific contraindications, interactions and reactions.
Further reading
What is levodopa used for?
Levodopa is used for Parkinson's disease. It addresses the motor symptoms of the condition by entering the central nervous system and converting into dopamine there.
How does levodopa work?
Levodopa crosses the blood-brain barrier and is then converted by an enzyme into dopamine, the neurotransmitter essential for smooth, coordinated movement. This replenishment addresses the deficit caused by the disease.
How long does levodopa take to work?
Levodopa usually starts to work within 30 to 60 minutes, and its effect lasts about 3 to 6 hours.
What are the side effects of levodopa?
Common reactions may include nausea, dizziness, dry mouth, or orthostatic hypotension, a drop in blood pressure when standing. Dyskinesia, sudden involuntary movements, can also develop as the body adjusts. Hallucinations are a serious effect and require immediate medical attention.
Can levodopa be taken with other medicines?
Concurrent use of other medications, particularly certain blood pressure agents or antipsychotics, can alter the efficacy of levodopa, and iron supplements can also interact with levodopa. Have your medicines reviewed by a doctor or pharmacist before combining them.
Who should not take levodopa?
Levodopa should not be used by anyone with hypersensitivity to its ingredients, narrow-angle glaucoma, or concurrent use of non-selective MAO inhibitors. Your medical history should be reviewed thoroughly to avoid contraindications, so check with a doctor or pharmacist.
In which products can I find levodopa?
Products containing levodopa include Sinemet, Sinemet CR and Stalevo. Compare forms, strengths and packs in the listings above.
What are other names for levodopa?
Besides the products listed here, levodopa is sold under brand names such as Caramet and Duodopa. Names differ from country to country, so the active ingredient is the surest way to compare.
Is levodopa available over the counter in Thailand?
Yes. In Thailand levodopa is sold by pharmacists without a prescription, and Yasabai does not ask for one either. We are an online store, not a dispensing pharmacy; we arrange your order and delivery on your behalf.
Ordering without a prescription →Can I order levodopa online in Thailand?
Yes. Our pharmacy partners ship from India to Thailand and across Asia in discreet packaging. Standard Airmail takes up to 3 weeks; Express Tracked Courier takes up to 1 week.
How ordering works →