Kombiglyze XR
Kombiglyze XR pairs saxagliptin with metformin in a prolonged-release tablet for type 2 diabetes mellitus, a DPP-4 inhibitor alongside a biguanide.
- Category
- Diabetes Management
- Active ingredients
- Saxagliptin · Metformin
- Route
- Oral use
- Form
- Prolonged-release tablet
- Strengths
- 5/500 · 5/1000mg
You will receive a quality branded generic or generic, depending on stock.
No prescription needed: we place your order for Kombiglyze XR on your behalf.
- Condition
- Type 2 Diabetes Mellitus
- Alternative names
- Kombiglyze
- Therapeutic class
- Dipeptidyl peptidase-4 (DPP-4) inhibitor and biguanide combination
- Pharmacological class
- Biguanide; DPP-4 inhibitor
- Contraindications
- diabetic ketoacidosis; renal impairment; hypersensitivity
- Minor side effects
- nausea; diarrhoea; gastrointestinal distress
- Moderate side effects
- urinary tract infection; headache
- Dosage forms
- Prolonged-release tablet
- Administration route
- Oral use
- Manufacturer
- AstraZeneca
- Onset time
- 1–2 weeks
- Duration
- Ongoing
- Storage instructions
- Store below 25°C.
- Drug interactions
- Alcohol; Cimetidine
- Age restrictions
- Not for children.
- Pregnancy and breastfeeding
- Pregnancy: Use is not recommended. Breastfeeding: Not recommended.
Precautions and warnings
risk of lactic acidosis; monitor renal function; watch for symptoms of pancreatitis
Serious side effects
lactic acidosis, requires immediate medical attention; pancreatitis, requires immediate medical attention
Patient summary
Kombiglyze XR pairs saxagliptin with metformin in a prolonged-release tablet for type 2 diabetes mellitus, a DPP-4 inhibitor alongside a biguanide.
Mechanism of action
Combines a DPP-4 inhibitor to increase insulin release and a biguanide to decrease hepatic glucose production and improve insulin sensitivity.
Kombiglyze XR combines Saxagliptin and Metformin to assist with the management of Type 2 Diabetes Mellitus. The same fixed-dose combination is also supplied as Kombiglyze. This medication from AstraZeneca is provided in extended-release tablet form, with available strengths ranging between 5/500 and 5/1000mg for specific requirements.
Buying Kombiglyze XR online
Generic versions containing Saxagliptin and Metformin are often significantly more affordable than the original brand, offering a practical solution for expats and those living in areas without consistent local supply.
What you will receive
Kombiglyze XR is the name this medicine is listed under. What you receive is a branded generic or generic with the same active ingredient (Saxagliptin / Metformin) at the same dose.
- We supply branded generics and generics only, mostly recognised Indian branded generics from vetted manufacturers, not originator brand packs.
- The exact brand and manufacturer depend on what is in stock at the dispatching warehouse.